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Subsequently, it was reported that not only is C3 binding to target tissues blocked by high levels of monomeric immunoglobulin, but C4 binding to target tissues is blocked as well [38].
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It has been reported that intravenous immunoglobulin blocks the binding of C3 to target tissues [38].
After vitamin D is converted to 25(OH D, 25(OH D binds to the vitamin D binding protein and is transported to target tissues through the circulation system.
In the circulation, ROH is attached to retinol-binding protein 4 (RBP4) and is transported to target tissues where it can be re-esterified or converted into its bioactive metabolites, which possess essential roles in vision and gene regulation.
JH binding protein (JHBP) can bind to JH and transport JH from the corpus allatum to target tissues [75].
CNTs serve as a platform for binding multiple molecular entities such as drugs for therapeutic purposes, marker molecules, cell-binding molecules, and molecules facilitating the transfer of drugs to target tissues.
The Takeout-like proteins, which are comprised of insect juvenile hormone-binding proteins and arthropod allergens, transport, where known, lipid hormones to target tissues during insect development.
Antibody variants that differ in antigen binding sites and size have been generated and evaluated as imaging probes to target tissues of interest.
In the bloodstream IGF1 binds to several IGF binding proteins (IGFBPs) which prolong its half-life and contribute to its delivery to target tissues[ 22].
The sex steroid hormone-binding globulin (SHBG) gene regulates the action of sex steroid hormones by modulating their bioavailability to target tissues such as the ovaries [ 4].
In contrast to target tissue biopsy, blood is not limited by restricted access to target tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com