Sentence examples for binding to target cells from inspiring English sources

Separating aptamer binding to target cells from FSNP binding to aptamer may allow a larger number of aptamers to bind to each target cell, amplifying the fluorescence signal.

MP carry at their surface proteins able to allow their binding to target cells, but also mediate cell cell interactions through cell adhesion molecules or simple contact.

A recent study [10], using challenges of vaccinated and naïve mice, has highlighted another, potentially significant element of the immune escape repertoire: the selection of 'adsorptive mutants', showing enhanced binding to target cells.

Previously most influenza HA antibodies have been found to recognize epitopes in the globular head and interfere with binding to target cells [6] [8], [33] [36], for example, the classical five antigenic sites (Sa, Sb, Ca1, Ca2, and Cb) [6], [7].

A dynamic model for CTT topology is consistent with the published studies by the Dimmock lab [16], [17] indicating that the KE is inaccessible to inactivation by SAR1 in free virions, but that the KE becomes exposed to SAR1 inactivation only after virion binding to target cells.

Insulin binding to target cells stimulates glucose uptake and increases glucose metabolism, in part through effects on gene expression.

Chemokines mediate their activities by binding to target cell surface chemokine receptors that belong to the large family of G protein-coupled, seven transmembrane (7 TM) domain receptors (also called serpentine receptors) (3).

In this regard, it has been demonstrated that the CPE290-319 COOH-terminus fragment is sufficient for high affinity binding to target cell receptor and small complex formation, although this fragment is incapable of initiating large complex formation and cytolysis [ 14- 16].

Increased parenchymal synthesis of C1q precedes blood brain barrier dysfunction [ 34], C1q can contribute to the endothelial expression of Vcam1 [ 36], C1q binding to target cell-bound NMO-IgG can trigger antibody-dependent and/or complement mediated cytotoxicity [ 37, 38], and the local activation of complement can trigger neutrophil recruitment [ 39].

Importantly, functional domain mapping of the full length 319-amino acid CPE protein demonstrated that the carboxy-terminal fragment (C-CPE290-319 peptise) isufficientnt for high-affinity binding to target cell receptors and small complex formation, although this fragment is not toxic because it is incapable of initiating large complex formation and subsequent cytolysis [ 15].

This supports that the 122-318 C-terminal part of Delta toxin contains the binding domain to target cells and that the N-terminal part is required for the cytotoxic activity.