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Extracellular adenosine exerts its effects by binding to surface receptors, of which the A2aR is predominantly involved with the anti-inflammatory and immunosuppressive activities10,21,22.
In 2011, Folding@home began simulations of the dynamics of the small knottin protein EETI, which can identify carcinomas in imaging scans by binding to surface receptors of cancer cells.
One possible way by which such antibodies can inhibit tumor growth is by binding to surface receptors that are involved in cell cycle regulation [25].
These results point to NADPH oxidase-regulated signaling events accounting for the differences in the inflammatory phenotypes between WT and p47phox−/− mice, rather than differences at the level of binding to surface receptors.
Aptamers and antibodies selectively deliver siRNAs to cells of interest by binding to surface receptors and then entering the cells by receptor-mediated endocytosis.
Studies by others suggest an active role for the NAPs, such as HA33 binding to surface receptors followed by internalization and transcytosis.
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These viruses infect specific bacteria by binding to surface receptor molecules and then entering the cell.
In addition, we show here that sFcεRI has the ability to prevent IgE-binding to surface expressed receptors.
Taken together, these results suggest that after entry into the respiratory or intestinal tract mucosa, EV71 is taken up into the microcirculation of local tissues and subsequently enters cells via binding to surface-expressed receptors.
This is because the assay is dependent on antibody (Ab) binding to cell surface receptors and redistribution to inclusions, so agonists could conceivably be increasing trafficking to the PM rather than internalization.
Upon binding to cell surface receptors, FGFs lead to activation of multiple signaling modules, including mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K), STAT1, and PKC.
More suggestions(11)
binding to α7 receptors
binding to serotonin receptors
binding to surface proteins
binding to surface structures
binding to histamine receptors
binding to surface nucleolin
binding to cognate receptors
binding to surface Fc-receptors
binding to lectin receptors
binding to surface blebs
binding to membrane receptors
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