Sentence examples for binding to such sites from inspiring English sources

Upon binding to such sites it displays enhanced fluorescence intensity [51].

Indeed, models considering the existence of binding to such sites show that the concentration of functionally-bound TF (i.e. to cis-regulatory regions) changes by a factor <2X when the TF concentration is either halved or doubled [ 29].

While perhaps premature to designate activation loop phosphorylations as an 'excluded group' in ANIA, 14-3-3 binding to such sites would probably not be compatible with kinase activity.

In addition Nrf2 undergoes post-translational modifications such as PKC-dependent phosphorylation on Ser-40, phosphorylation through the MAPK/ERK signaling pathways in response to endoplasmic reticulum/unfolded protein stress or by casein kinase and CBP/p300 also promoting its binding to such ARE sites.

Effector binding to such a binding site in another layer is performed by introducing a new species that represents the sum of all microscopic species with phosphorylated but unoccupied binding sites.

The binding of noble gases within two double mutants was studied to characterize the additivity of binding at such sites.

Many of the NCAs that bind in the pore inhibit the 5-HT3R blockinging the channel, but allosteric modulators can also influence channel gating by binding to sites such as the inter-subunit region at the extracellular ends of the TMD α-helices (Trattnig et al., 2012).

While binding to some sites such as stem IIB or IA can show substantial specificity even in their isolated contexts, this does not seem to be the case for the remaining Rev binding sites (Daugherty et al., 2008).

In an attempt to address part of this potential problem with reversibility, glycosylated dendrimer was used in this system to avoid the increased binding affinity from a tetrameric unit of Con-A binding to multiple sites, such as what may occur for a long chain like dextran, and by using Alexa Fluor 647 which is more resistant than other fluorophores, such as the rhodamine dyes, to photobleaching.

Thus, while it is unable to signal from an internal duplex, RIG-I is still capable of binding such sites at very high concentrations.

Dr. Soufi showed that Oct4, Sox2 and Klf4 act as pioneers, engaging silent, DNase-resistant chromatin sites that lack known histone modifications, whereas c-Myc is dependent upon pioneer factors for binding such sites.