Sentence examples for binding to specific sites from inspiring English sources

Many reports have described transcription factors regulating gene expression by functionally coordinating with cis-elements (Raff and Kaufman 1991; Wilkins 1991; Gerhart and Kirschner 1997; Carroll et al. 2001) and binding to specific sites (Levine and Tjian 2003).

It is now generally accepted that many of the physiological effects of alcohol consumption are a direct result of binding to specific sites in neuronal proteins such as ion channels or other components of neuronal signaling cascades.

The same was observed for the H-2Kb/OVAp surface expression indicating that there was no competition of these antibodies for binding to specific sites.

A key step in the mode of action of Bt insecticidal Cry proteins is the binding to specific sites in the brush border membrane of the larval midgut [35], [36].

MicroRNAs have been shown to inhibit translation or decrease mRNA stability by binding to specific sites usually in the 3' untranslated region (UTR) of target messages, thus providing another layer of control of gene expression [5], [6], [7], [8].

They commonly act as negative regulators of the expression of protein coding genes, usually recognizing and binding to specific sites in the 3'UTRs of their mRNAs, and impairing their translation, or sometimes even inducing the degradation of the target mRNA (for an exhaustive review, see [2].

miRNAs, a group of small non-coding RNAs, regulate gene expression by binding to specific target sites on messenger RNA to either repress or degrade targets.

The GRα complex can directly or indirectly alter gene transcription by binding to specific DNA sites or by activating transcription factors.

The encounter of a Ca2+ ion with a protein and its subsequent binding to specific binding sites is an intricate process that cannot be fully elucidated from experimental observations.

MiRNAs mediate gene silencing by binding to specific target sites within the 3'UTR of mRNA to either block translation or to bring about degradation of transcripts.

The activated Stats then dimerize, translocate to the nucleus, and participate in transcriptional regulation by binding to specific DNA sites.