Sentence examples for binding to specific sequences from inspiring English sources
MicroRNAs are small 18 to 22 nucleotide long RNA molecules, which negatively regulate expression of target genes by binding to specific sequences in 3'UTR where partial complementarities inhibit their translation and perfect complementarily induces degradation of mRNA [28], [29].
HIFs activate hypoxia-responsive genes by binding to specific sequences in their promoter regions called hypoxia-responsive elements (HRE); a number of HRE have been analyzed and the consensus sequence is 5'-RCGTG-3', where R is A or G, although variants have been reported[4].
These proteins coregulate transcripts by binding to specific sequences and secondary structures that mediate these processing steps.
MiRNAs regulate gene expression through translational repression of mRNA by promoting the degradation of mRNA by binding to specific sequences in the untranslated regions of the mRNA.
The native function of TALEs is to modulate host gene expression by binding to specific sequences in host gene promoters and activate transcription [ 5, 6].
They activate transcription of host genes by binding to specific sequences in the promoter region of the targeted gene [ 8, 9].
Interestingly, optimization of zinc finger protein amino acid sequences for high-affinity binding to specific DNA sequences results in proteins with little or no predicted specificity, suggesting that naturally occurring DNA-binding proteins are optimized for specificity rather than affinity.
TFs are families of small proteins that regulate gene expression by binding to specific promoter sequences.
A transcription factor binding to specific DNA sequences controls the rate of transcription of genetic information from DNA to messenger RNA (Todeschini et al. 2014).
Transcription factors (TF) regulate expression by binding to specific DNA sequences.
The Pax gene family contains nine members characterised by the presence of a common paired-box domain that directs binding to specific DNA sequences.
