Sentence examples for binding to specific response from inspiring English sources
The manner in which PPARs regulate gene expression includes association with retinoid-X-receptor (RXR) and binding to specific response elements found on target genes.
Transcription factors activate their target genes by binding to specific response elements.
Phosphorylated STAT proteins homo- or hetero- dimerize and translocate to the nucleus to activate transcription of target genes by binding to specific response elements in their promoter regions.
The classical mechanism of ER action involves estrogen binding to nuclear receptors followed by receptor dimerization and binding to specific response elements known as estrogen response elements located in the promoters of target genes.
The androgen receptor regulates the transcription of specific target genes by binding to specific DNA response elements in their promoters, referred to as androgen response elements (AREs) [25], [26].
Nuclear hormone receptors are ligand-activated transcription factors that modulate gene expression through binding to specific hormone response elements.
Heterodimerisation of PPAR γ and retinoid X receptor (RXR) is required for binding to specific DNA response elements of target genes.
Progesterone binding induces a conformational change(s) in PR that promote dissociation from a multiprotein chaperone complex, homodimerization, and binding to specific progesterone response elements (PREs) within the promoter of target genes [ 72, 73].
The bound androgen receptor acts as transcription regulatory element by binding to specific DNA response elements in target gene promoters, causing activation or repression of transcription and subsequently protein synthesis.
Progesterone classically signals by binding to intracellular progesterone receptors (PR), leading to receptor dimerisation and binding to specific hormone response elements located in the promoter region of target genes to regulate transcription through interaction with co-regulatory proteins (Mulac-Jericevic & Conneely 2004, Shao et al. 2006, Gellersen et al. 2009).
However, ecdysone binding to the EcR-USP complex controls transcription through direct binding to specific Ecdysone-response elements in the regulatory regions of the target genes (Thummel, 1996).
