Sentence examples for binding to specific phosphorylated from inspiring English sources

They operate by binding to specific phosphorylated residues on target proteins.

IRS proteins thus act as molecular adapters in recruiting, inter alia, a number of SH2-containing proteins binding to specific phosphorylated tyrosine residues.

They operate by binding to specific phosphorylated sites on such diverse target proteins as oncogene products, tumour suppressor proteins, and regulators of cell survival, proliferation and growth [ 52]. 14-3-3s associatedassociated with dynamic nucleo-cytoplasmic shuttling.

14-3-3's are a family of conserved proteins that control many diverse processes by binding to specific phosphorylated sites on target proteins to induce changes in the target conformation or to change the target's interactions with other proteins [ 86].

This specific comment was meant to reinforce that the rather subtle differences observed between E2F2 and E2F3 binding to specific mono-phosphorylated Rb isoforms was consistently observed in three independent experiments, whereas E2F1 and E2F4 showed much larger binding differences.

Upon HS, HSF1 is phosphorylated, liberated from Hsp90, undergoes trimerization and translocates to the nucleus to activate target gene expression by binding to specific heat-shock elements (HSE) in target promoters.

Phosphorylated STAT proteins homo- or hetero- dimerize and translocate to the nucleus to activate transcription of target genes by binding to specific response elements in their promoter regions.

Tyrosine phosphorylated STAT monomers engage in dimerization through a reciprocal pTyr-SH2 domain interaction, creating transcriptionally active STAT:STAT dimers that in the nucleus regulate gene expression by binding to specific DNA-response elements in the promoters of target genes.

However, Sas6 showed a dramatic increase in binding to Ana2 phosphorylated by Plk4.

It is tempting to speculate that Atg13 may function as a molecular switch that changes conformation after binding a specific phosphorylated substrate or phospholipid.

Specific binding to active phosphorylated receptor was the first arrestin function discovered (Kuhn et al., 1984).