Sentence examples for binding to specific membrane from inspiring English sources
It is reported that interferons exert their activities mainly by binding to specific membrane receptors on the cell surface.
The predominant Bt toxins in Bt crops are crystalline (Cry) proteins that kill insects by binding to specific midgut membrane target sites and disrupting membrane integrity (Schnepf et al. 1998).
Interferons (IFNs) are a family of secreted cytokines [ 1, 2] that exert their biological activities by binding to specific cell membrane receptors to trigger a well characterised intracellular signalling pathway [ 3, 4] culminating in the transcriptional induction of IFN stimulated genes (ISGs).
Previously, we demonstrated that tail anchors in DMPK A/B and DMPK C/D drive binding to specific organellar membranes [9].
Phosphoinositides are important membrane lipids that regulate cell growth and survival, cell division and membrane trafficking through recruiting and activating effector proteins and enzymes that contain phosphoinositide-binding domains, to specific membrane microdomains [ 30].
After binding to specific, yet unknown, membrane acceptor(s) ET undergoes a cholesterol-dependent heptamerization leading to the formation of a transmembrane pore [8] [12].
Discrete Aβ binding events correlate to specific membrane permeation events.
ECM is composed of a complex mixture of macromolecules and a variant of secreted molecules, such as growth factors, that through binding to specific ECM molecules and membrane receptors may activate signalling pathways that control or alternate cell behaviours [ 4].
Chemokines are a family of pro-inflammatory peptides (8-15 kD) that are produced locally in tissues and mediate leukocyte and microglia directional migration and activation during inflammatory reactions by binding to specific chemokine receptors in the membrane of their respective target cells.
They act by binding to specific receptors in the plasma membranes of target cells, thereby activating signal transduction mechanisms (Köveker 2000; Cavanagh et al 2005).
A key step in the mode of action of Bt insecticidal Cry proteins is the binding to specific sites in the brush border membrane of the larval midgut [35], [36].
