Sentence examples for binding to specific karyopherin from inspiring English sources

The majority of proteins with nuclear function are actively transported based on its binding to specific karyopherin receptors usually by the presence of NLS and NES signals.

TFs are families of small proteins that regulate gene expression by binding to specific promoter sequences.

Ran-GTP provides an important source of energy to the reaction by binding to karyopherin β as it enters the nucleus with karyopherin α and cargo in tow, releasing the cargo to the nucleoplasm.

Non-specific binding was subtracted from total binding to obtain specific binding.

Importin, a karyopherin, is involved in the transportation of protein molecules into the nucleus by binding to a specific recognition sequence, called the nuclear localization signal (NLS) [ 46].

It therefore appears that overexpression of Lhp1 from a plasmid interferes with the ability to detect binding to its partner Karyopherin.

Non-specific binding obtained by incubating 1 mM L- glutamate in the binding assay was subtracted from total binding to yield specific [3H] AMPA- binding.

In all experiments, nonspecific binding was determined and subtracted from total binding to obtain specific binding.

Similarly, PY-NLS binding to Karyopherin-β2 (also known as Transportin-1) involves mostly the NLS side chains, and we may observe these NLSs binding to Karyopherin-β2 in the opposite orientation in the future (Lee et al., 2006; Soniat et al., 2013).

Nuclear localization of large proteins, such as LANA, requires a nuclear localization signal (NLS) that mediates binding to members of the karyopherin family of nuclear transport proteins.

At larger probe intensities, non-specific binding becomes less important compared to specific binding.