Sentence examples for binding to specific genomic from inspiring English sources

The CXXC domains are important for TET proteins binding to specific genomic regions for their action (Xu et al., 2012; Tan and Shi, 2012; Jin et al., 2014), and they can cooperate with the catalytic domain to regulate the key gene expression (Xu et al., 2012; Ko et al., 2013).

One widely supported theme is that DNA methylation can impede TF binding to specific genomic fragments [11], [12].

Gene regulatory processes are largely resulting from binding of transcription factors to specific genomic targets.

The binding of MOZ/MORF complexes to specific genomic regions and their activity are modulated by posttranslational histone modifications.

The two engineered nucleases are composed of programmable and sequence-specific DNA-binding modules, which bring the nucleases to specific genomic site to introduce a DNA double-strand break.

Steroids may exert their action by genomic pathways, involving hormone binding to specific nuclear receptors (NRs) and subsequent modulation of gene transcription after binding to DNA.

Hence, the core PRC2 proteins interact with accessory proteins, such as Jarid2, Aebp2 or members of the polycomb-like (Pcl) family encoding Phf1 (Pcl1), Mtf2/Pcl2 and Phf19 (Pcl3) that contain DNA binding domains able to target the PRC2 to specific genomic loci4,5,6,7.

These results suggest that in addition to their roles in recruiting protein complexes to specific genomic loci, lncRNA binding may also regulate the longevity of their interacting protein complexes.

Although the CUX1 consensus binding motif, ATCRAT, plays a role in the recruitment of CUX1 to specific genomic sites, protein-protein interactions must contribute to its transcriptional activity.

We conclude that the presence of a CUX1 consensus binding site contributes to, but is not sufficient for, the recruitment of CUX1 to specific genomic locations.

Do general anaesthetics act by competitive binding to specific receptors?