Sentence examples for binding to specific death from inspiring English sources

TNF-α (tumor necrosis factor alpha): Cytokine binding to specific death receptors.

Apoptosis can be initiated in several ways, for instance by ligands binding to specific death receptors, like the TNF receptor family, by cellular stress through DNA damage, or by deprivation of growth factors or nutrients [ 19, 20].

In particular, after cerebral infarction, in neurons of the core area the first apoptotic events are mediated by ligand binding to specific death receptors leading to caspase 8 activation.

Apoptosis, or programmed cell death, is a series of well coordinated and strictly controlled processes in which ligand binding to specific (death) receptors or cytotoxic insults result in the activation of several proteases and other hydrolytic enzymes, leading to proteolysis, DNA fragmentation and chromatin condensation [ 5].

Apoptosis involves two main pathways: the extrinsic pathway, initiated by binding of ligands to specific death receptors, and the intrinsic pathway, initiated at the mitochondria [21], [22].

External signals are mediated via binding of ligands such as FAS, TNF, or TNFSF10/TRAIL to specific death receptors present on the cell surface triggering receptor oligomerization and assembly of intracellular multiprotein complexes such as the death inducing signaling complex (DISC).

The produced cytokines can trigger innate or adaptive immune responses by binding to specific receptors on macrophage and other immune cell surfaces and resulting in host defense, cell growth, differentiation, and cell death.

Do general anaesthetics act by competitive binding to specific receptors?

Gene expression (transcription) is generally regulated by TFs binding to specific sites.

Each controls the expression of numerous genes by binding to specific regions in the genome.

Glutamate exerts its effects by binding to specific receptors on nerve cells.