Sentence examples for binding to specific cell from inspiring English sources

The various cone shell toxins are designed to interfere with a victim's nervous system and work by binding to specific cell surface receptors (glycoproteins) and ion channels.

However, subsequent studies revealed that HA also exerts important biological effects by binding to specific cell surface receptors and other extracellular matrix (ECM) molecules, which initiates intracellular signaling cascades that modulate key functions such as adhesion, migration and proliferation.

All those mutants were biologically competent in several cell culture assays, maintaining typical FGF-1 activities, such as binding to specific cell surface receptors and activation of downstream signaling pathways.

Exotoxin A of Pseudomonas aeruginosa asserts its cellular toxicity through ADP-ribosylation of translation elongation factor 2, predicated on binding to specific cell surface receptors and intracellular trafficking via a complex pathway that ultimately results in translocation of an enzymatic activity into the cytoplasm.

As a result, particle surface and internal porosity have been designed to meet criteria‐facilitating passive targeting (e.g., for pulmonary delivery), modification of the drug release profile (e.g., attenuation of the burst release) and active targeting via ligand binding to specific cell receptors.

The accepted view of cell signaling by secreted proteins is that cell-cell communication is mediated by ligands binding to specific cell surface receptors that transmit an intracellular response.

Many viruses, bacteria, and protein toxins adhere to their target cells by binding to specific cell-surface carbohydrates.

VEGF stimulates proliferation and tube formation of vascular ECs (endothelial cells) by binding to specific cell-surface receptors.

VEGF and PDGF are two of several molecules that promote angiogenesis by binding to specific cell-surface tyrosine kinase receptors (TKRs) [ 7, 8].

VEGF is one of the most potent inducers of vascular permeability, and specifically targets ECs through binding to specific endothelial cell surface receptors, including VEGFR-1 and VEGFR-2.

Recently, it has been proposed that LcrV from Y. pestis exhibits IFNγ-dependent binding to specific monocytic cell lines [28].