Sentence examples for binding to small molecules from inspiring English sources

19F NMR has recently emerged as an efficient, sensitive tool for analyzing protein binding to small molecules, and surface plasmon resonance (SPR) is also a popular tool for this purpose.

A few cases of nucleic acids binding to small molecules in solution have been demonstrated by capturing aptamer onto a streptavidin sensor surface directly or via hybridization.

Motif M3 was found to be a part of aptamer structure (the region binding to small molecules) of FMN riboswitches [ 38, 39].

Rice Hbs could potentially function within cells through O 2-transport and -signaling, binding to small molecules (most notably NO) and other as yet undetermined mechanisms.

To address this limitation, we developed and validated a high-throughput and scalable SPR-based strategy for characterizing aptamer binding to small molecules.

The ability of a protein to bind small, drug-like molecules with a high affinity is referred to as "druggability" (ligandability often refers to the more general ability of binding to small molecules).

Residues lining the inhibitor binding pocket are strictly conserved between ALK1 and ALK2 explaining their common binding to small molecule BMP inhibitors, including K02288 (Fig.  1c) [ 16].

Furthermore, these methods consider many aspects of protein molecular function including binding to small organic molecules, inorganic groups, for example, iron-sulfur clusters and metal ions, and interactions with nucleic acids and other proteins [ 17].

Hfq is a small abundant RNA-binding protein that functions as a global posttranscriptional regulator of gene expression by binding to small regulatory RNA molecules (sRNAs) and facilitating their interaction with mRNA molecules [45].

Here we report an improved platform for characterizing binding properties of aptamers to small molecules.

We report the development of a surface plasmon resonance-based platform for rapid characterization of kinetic and equilibrium binding properties of aptamers to small molecules.