Sentence examples for binding to serum components from inspiring English sources

Despite the potent oncolytic activity of these peptides in vitro, studies in vivo are very limited, mainly because of their inactivation in serum, partially because of their binding to serum components and their enzymatic degradation.

Peptide degradation in serum owing to the presence of proteases is a major obstacle, which besides unspecific binding to serum components also limits the half time of these molecules in serum.

Further, autoantibodies to serum components acting as bridging molecules (for example, C1q, mannose-binding lectin, serum amyloid P component, and C-reactive protein) have been detected in patients with SLE [ 18, 19].

Tight ruthenium binding to serum albumin was established by joint use of spectroscopic and separation methods.

By means of simple binding between serum components and calcium and phosphate, we are now able to demonstrate a plethora of NB-like morphologies that include round, laminated particles, spindles, and even films [3].

Phage-based assays are mostly performed in an ELISA format; however, if complex substances such as serum are used in detecting targets, this approach lacks sensitivity due to aspecific binding of interfering serum components increasing the background signal.

Richards, D. B. et al. Therapeutic clearance of amyloid by antibodies to serum amyloid P component.

In addition, chemically modified serum components that contribute to serum ThT fluorescence were explored and identified.

The biological consequence of the binding of cis-dichlorodiammineplatinum II) (cis-dichlorodiammineplatinum IIll as to cellular componento in general, waserumdied on human NHIK 3025 cells in vitro.

(b) Assessment of Nb.b201 binding to human serum albumin by surface plasmon resonance, comparison with mouse serum albumin which shows no detectable binding.

We also found that serum blocked binding of mycobacteria to both wild type and SR-B1−/− alveolar macrophages and BMDmØ (data not shown) as opposed to an earlier observation where serum components increased binding to BMDmØ [31].