Sentence examples for binding to phosphorylated sequences from inspiring English sources

Thus, binding to phosphorylated sequences is a crucial property of Bub3.

Similarly, Itk requires binding to phosphorylated SLP-76 to maintain its active conformation [13].

Importantly, this ubiquitination event does not aect Smad4 stability but inhibits its binding to phosphorylated Smad2.

Moreover, tumor-associated mutations in the BRCT domains of BRCA1 abolish binding to phosphorylated substrates.

SOCS3 inhibits leptin signaling by binding to phosphorylated tyrosine residue of the leptin receptor (22).

They function primarily by binding to phosphorylated proteins [ 7], although other modes of binding have been reported [ 8– 11].

The SH2-domain is capable of binding to the phosphorylated ITAM sequences of the FcεRI β-chain and FcRgamma [ 62, 63].

Biochemical and structural studies have suggested that the Numb PTB domain is capable of binding to either non-phosphorylated sequences that contain an NXX[Y/F] motif or pTyr-containing sequences [ 104, 111, 116, 117].

Specific binding to active phosphorylated receptor was the first arrestin function discovered (Kuhn et al., 1984).

The binding to active phosphorylated GPCRs was long considered the only function of arrestins.

However, Sas6 showed a dramatic increase in binding to Ana2 phosphorylated by Plk4.