Sentence examples for binding to overlapping from inspiring English sources

Binding of other proteins is also expected to affect detectability, negatively if the two proteins compete for binding to overlapping sites, or positively if the two proteins bind cooperatively.

Here, we report that the Amm VIII protein elicits antibodies that only recognize discontinuous-type epitopes since we could not observe any antibody binding to overlapping 12-mer peptides covering the whole Amm VIII sequence.

The competitive inhibition of binding to overlapping epitopes has been described for antibodies to ACE.

In one case, the two proteins appear to compete for binding to overlapping sites [ 45].

The protein Dead end 1 (Dnd1), on the contrary, blocks miRNA-mediated silencing by competitive binding to overlapping sites [ 37].

These results support the previous findings that Snail and SIP1 directly repressed E-cad promoter activity by binding to overlapping three E-box CACCTG sequences (Batlle et al, 2000; Comijn et al, 2001).

E2F proteins, which share a conserved DNA binding domain, can bind to overlapping sets of target promoters.

Antibodies binding to epitopes overlapping the CD4-binding site on gp120 are potent inhibitors of HIV entry, such as the llama heavy chain antibody fragment VHH D7, which has cross-clade neutralizing properties and competes with CD4 and mAb b12 for high affinity binding to gp120.

While overexpression may increase the number of binding events, we would expect the majority of endogenous ZEB1 binding sites to overlap with those detected using ZEB1-HA ChIP. ZEB1-HA ChIP

The influence of these polymorphisms (rs945032 and rs1799722) indicate that any given functional variation within a regulatory region might exert a measurable influence within the context of a cell type determined by the TF expression profile of the cells and perhaps competitive binding of the TF to overlapping multiple binding sites.

Propagation of MLL1 association with DNA may arise from a combination of two molecular events: binding of MLL1 to overlapping morphemes and MLL1 oligomerization via the SET domain.