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Leukotrienes comprise a family of products of the 5-lipoxygenase (5-LOX) pathway of arachidonic acid metabolism binding to outer plasma membrane receptors [ 23].
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The translocation of phosphatidylserine, one of the markers of apoptosis, from the inner to the outer plasma membrane was detected by binding of allophycocyanin (APC -conjugated APC -conjugated4T cells were plAnnexinto plates, treated with drugs for 24 h and stained with mouse anti-human Annexin V.antibody and propidium iodide (PI).
Phosphatidylserine, which is normally confined to the inner leaflet of the plasma membrane, is exported to the outer plasma membrane leaflet during apoptosis.
In early apoptotic stage phosphatidylserine (PS) makes way to the outer plasma membrane leaflet.
Calreticulin translocation to the outer plasma membrane was analysed as described [49].
Native PrP (PrPC) is bound to the outer plasma membrane.
PS externalisation to the outer plasma membrane is a well-known characteristic of apoptosis.
It is not fully understood how and why cancer cells expose PS to the outer plasma membrane leaflet.
The nature of this inhibition was characterized by studies of [3H]cytochalasin B binding to liver plasma membranes.
MA (Protein Data Bank (PDB) accession 1HIW 37 is involved in Gag targeting and binding to the plasma membrane, and in incorporation of the envelope (Env) glycoprotein.
Figure 1 Effects of silica particle size on binding to human plasma proteins.
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