Sentence examples for binding to nuclear matrix from inspiring English sources

South-western assays [ 19, 20] and PCR based assays [ 21] have also been used successfully to show S/MAR binding to nuclear matrix.

The MAR element, which consists of AT-rich DNA, makes an independent loop or domain in the chromatin by binding to nuclear matrix proteins such as topoisomerase II, histone H1, lamins, SP120, ARBP, and SATB1.

4 of the S/MARs which were seen to be associated with the nuclear matrix in the PCR based assay did not show binding to nuclear matrix in the south western assay (GlSMAR11, GlSMAR39, GlSMAR42, GlSMAR55).

Matrix attachment region DNAs (MAR) are DNA sequences that bind to nuclear matrices after being digested by restriction enzymes.

In Entamoeba, such S/MARs were found to have reduced binding ability to nuclear matrix compared to the ones that were present outside ORF (our unpublished data).

Scaffold/Matrix Attachment Regions (S/MARs) are eukaryotic DNA sequences capable of specific binding to nuclear proteins that are part of the nuclear matrix.

NF-κB is a cytosolic transcription factor binding to nuclear DNA and activating transcription of target genes.

Both structures serve to mediate binding to nuclear transport proteins.

For example, the relation between TBP and nuclear matrix binding sites has been discussed for a long time and in some reports these are claimed to be identical structures [ 32- 34], others consider TBP-DNA complexes to be specific structures, not related to nuclear matrix attachment sites [ 2, 35].

The episomal replication is due to stable association with early replication foci by MARS mediated binding to the nuclear matrix protein scaffold attachment factor A (SAF-A).

Alternately, GlSMAR58 and GlSMAR16 showed binding to the nuclear matrix by southwestern though it was not amplified from the matrix dependent pool in the PCR based assay.