Sentence examples for binding to nuclear components from inspiring English sources

Mutations in the NLS or enhanced binding to nuclear components may account for pronounced nuclear survivin (Engels et al, 2007).

That CaM's role is almost certainly in nuclear entry rather than in facilitating SRY nuclear retention is consistent with the fact that SRY nuclear accumulation does not appear to involve binding to nuclear components [ 13] and that the CaM-NLS alone is sufficient to target even large carrier proteins to the nucleus [ 10, 35].

Highly conserved mechanisms could be involved in organotin binding to nuclear receptors, membrane components and intracellular proteins as well as in promoting DNA damage, all widely shared action modes of these toxicants.

NF-κB is a cytosolic transcription factor binding to nuclear DNA and activating transcription of target genes.

The down-regulation by E2 predominantly arose via binding to nuclear ERs.

Both structures serve to mediate binding to nuclear transport proteins.

This binding could be competitively inhibited by excess unlabeled HepcARE (lane 5); mutant HepcARE could not bind to the nuclear component and compared with control we found only modest binding in nuclear extracts from cells treated with FeSO4 (Fig. 6 A, lanes 2and 9 respectively).

One way to interpret the output of sequencing studies is to investigate how the element of interest localizes in relationship to genome annotations and the binding of other nuclear components.

In the last 20 years, studies on nuclear actin became fashionable, and now a new area began which firmly established actin, its relatives and binding partners as nuclear components.

The etiology of autoimmunity is complex, either the cross-reactivity by anti-pp65336-439 antibody to multiple nuclear components or epitope spreading by binding of pp65 to host proteins may contribute to the out spread of auto-reactive antibodies.

Although we do not yet know how sumoylation facilitates the nuclear localization of lipin-1α in neuronal cells, sumoylation might influence its nuclear localization by controlling interactions with the nuclear import/export machinery, and/or by regulating its binding to intranuclear components.