Sentence examples for binding to multiple ligands from inspiring English sources

Many receptors function by binding to multiple ligands, each eliciting a distinct biological output.

In addition, CheY6 from R. sphaeroides, discussed shortly, may be a paradigm for a specific type of CheY which may be capable of binding to multiple ligands.

RAGE binds multiple structurally diverse ligands and is considered a pattern recognition receptor, but the structural basis for RAGE binding to multiple ligands is not well understood.

Proteins that are involved in these processes act as 'universal adapters' by binding to multiple ligands and connecting otherwise disconnected ligands to each other.

In the case of another endothelial cell receptor, LSECtin, glycan array screening at high receptor concentration reveals binding to multiple groups of ligands with terminal fucose and GlcNAc residues, but at reduced concentrations much more selective binding is observed to glycans bearing terminal GlcNAcβ1-2Man disaccharides (Powlesland et al. 2008).

This method yields a metric that quantifies the influence on overall ligand affinity of ligand binding to multiple, distinct sites within a protein binding region.

It has been confirmed that the high affinity and specificity of binding to typical ASGP ligands are the result of multiple carbohydrate recognition domains in a hetero-oligomeric ASGPR complex binding to multiple complementary Gal/GalNAc residues in a glycan ligand containing multiple nonreducing termini [21], [22].

Myriad interactions in nature use polyvalent binding, where multiple ligands on one entity bind to multiple receptors on another: antibody antigen interactions, virus−cell binding, cell cell signaling, and others.

The simultaneous binding of multiple ligands to multiple cellular receptors can lead to receptor clustering.

The binding of multiple ligands to individual receptors has previously been described [ 39]; however, certain interactions appear to be more important than others.

How binding of multiple ligands to receptors shapes dose responses.