Sentence examples for binding to mast cells from inspiring English sources

Unlike conventional drugs, anti-IgE works by blocking the IgE from binding to mast cells.

Complement C3a is highly biologically active, binding to mast cells and basophils and triggering release of their vasoactive contents (the des-arg form represents a stable inactivated form of complement C3a).

Although IgG1 is capable of binding to mast cells and could provide the anaphylactic trigger [ 13], a previous report using the same EAE model as we have used here has clearly implicated IgE and ruled-out IgG1 [ 6].

We describe the design, synthesis, and characterization of a heterobivalent ligand (HBL) system that competitively inhibits allergen binding to mast cell bound IgE antibody, thereby inhibiting mast cell degranulation.

It would decrease due to competitive inhibition of IgE anti-ragweed binding to mast cell receptor sites by myeloma IgE.

Because natural IgE can bind to mast cell FcεRI and impact mast cell functions 5– 7, we sought to investigate what effect IL-33 and IL-33-derived IgE may have on mast cell function in naïve mice.

Elicitation of an allergic reaction occurs when a sensitized individual is re-exposed to a food allergen under conditions that allow sufficient binding to occur between the allergen or its fragments and allergen-specific IgE antibodies bound to mast cells and basophils such that physiologically active mediators of allergic disease are released from these mast cells and basophils.

Intragraft CD4+ cells were close to mast cells in morphology.

Like IL-18, some activity of IL-33 is related to mast cells.

Perhaps the most compelling data regarding immune activation relate to mast cells.

Most angiogenic mediators released by mast cells are not exclusive to mast cells, so it is difficult to attribute their biological actions to mast cells alone.