Sentence examples for binding to its respective from inspiring English sources
Indeed, in thioglycolate-recruited macrophages infected with L. major, very little NF-κB was available for binding to its respective DNA elements (22).
The inhibition of TCDD-mediated COX-2 activation by treatment with zerumbone appears to be the result of its interference with C/EBP-β binding to its respective DNA binding element (Fig. 3b).
Peptide aptamers, molecules designed to selectively bind to a given target protein and block its activity in vivo, have been effectively used to inhibit E6 binding to its respective partners, resulting in increased p53 levels and the apoptotic elimination of HPV-positive SiHa cells [ 15].
Furthermore, IL-1 binding to its respective receptor initiates a mitogen-activated protein (MAP) kinases pathway, such as the p38 pathway, which is also activated by binding to TLRs and to the TNF receptor, and which will promote the transcription of adhesion molecules [ 283].
They are, however, computationally much more expensive, with a nontrivial chance of not yielding any answer to the problem, as diffusion and binding of the substrate to its respective binding site might take a long time.
After removing unbound fluoroliposomes by extensive washing, only gels containing receptor-bound ligands emitted fluorescence under ultraviolet light in the dark field (Fig. 2a), suggesting binding of each ligand to its respective receptor on the liposome surface.
In construction of an HtBv ligand the covalent modification by which two targeting moieties are linked should have a minimal effect on the binding of each moiety to its respective target.
The binding of a HER ligand to its respective receptor leads to conformational changes in the receptor's extracellular domain which allow the formation of homo- and/or heterodimers between different members of the ErbB family.
Such association may result in a stimulation of the ClaR regulator and allows its binding to the respective DNA regions, resulting in ClaR-dependent regulation of gene expression.
Binding kinetics studies revealed that mAb 2F5 and 4E10 binding to their respective gp41 peptide-lipid conjugates could best be defined by a two-step (encounter-docking) conformational change model.
