Sentence examples for binding to its own from inspiring English sources

Chromatin immune precipitation and transcriptional analyses showed that HBR increased the transcription of the cardiogenic gene Nkx-2.5 through Smad4 binding to its own consensus Smad site.

Once expressed in response to RA, RARβ2 sustains its own transcription by binding to its own promoter [6], and subsequently activates the chromatin of other downstream RA-responsive direct target genes [7], [8].

Protein A exhibits an auto-regulatory loop by binding to its own promoter, as well as a cross-regulation mediated by protein B. Gene B expression is analogously regulated (see figure 1).

In mice, sox9 is able to autoregulate by binding to its own promoter.

NFATc1 autoamplifies its own gene, possibly by binding to its own promoter [ 35].

SRF autoregulation by binding to its own promoter and binding to the co-activator MKL1 were clearly observed.

This antagonistic conformation of H12 is different from that observed in the structure of the RXRα-oleic acid in the fully antagonist RARα/RXRα heterodimer, where H12 of RXRα in complex with oleic acid binds to its own cofactor binding site [12].

This revealed significantly increased binding of PGC1α to its own promoter and unexpected binding to the Drp1 promoter (Fig. 3E).

While binding of Oct4 to its own promoter has a positive regulatory effect, its binding to the Cdx2 promoter is suppressive.

The binding of Pfk2p to its own message could provide an additional layer of expression regulation by controlling the translation, localization or the stability of the message.

(ii) The Oct4-Cdx2 heterodimer are repressors on both Oct4 and Cdx2, where the latter activates itself through the binding of Cdx2 to its own promoter [12].