Sentence examples for binding to its negative from inspiring English sources

However, p53 phosphorylation prevents p53 from binding to its negative regulator MDM2 [ 35].

MiR-30e and miR-181d were identified as posttranscriptional negative regulators of HtrA1 by binding to its 3′ untranslated region.

We therefore speculate that the positively charged surface of kurtoxin is an important determinant of its binding to the conserved negative domain in Cav3 (T-type) Ca2+ channels.

Surprisingly, we observed that ligand (T3) weakens TR binding to a negative regulatory element (NRE) present in the TSHβ promoter.

Note that the non-specific binding to the negative control sequence (CRE, cAMP response element) is within this latter range of affinities (Kd = 6.6 µM).

Binding to positive glucocorticoid response elements as a homodimer results in transcriptional activation; and binding to negative glucocorticoid response elements results in transcriptional inhibition [ 26].

Specific (circle) and non-specific binding (triangle) (binding to negative control Colo16 cell line) of 125I-chAb 14C5 (a), of 125I murine Ab 14C5 (b), of 125I-chF ab' 2 125I-chF ab' 2of 14C5-chFand14C5 (d).

Figure 10 illustrates SEB binding to negative control electrodes that lacked capture Ab and were blocked with casein.

Consequently, they are readily accessible for binding to molecules with negative charges, e.g., nucleic acids.

Negative or counter selections are often performed to increase the specificity of the library or direct the enrichment process away from binding to negative targets.

Immunoblotting, immunofluorescence, and flow cytometry revealed specific binding of CA125-targeting vectors to NIH OVCAR-3 cells aNIH OVCAR-3ng to antigen-negative SKOV3 cells.