Sentence examples for binding to its membrane from inspiring English sources

DENV, JEV, and WNV were tested to interact with the light chain of dynein (Tctex-1) by binding to its membrane protein.

H-histamine binding to its membrane receptors which leads to lower H-histamine dilution profiles in respect to reference molecule and/or cellular internalization of H-histamine (i.e., cellular uptake) which can be estimated by the BF.

This means that glucagon during anaphylaxis reduced the level of endogenous histamine, which led to increase of exogenous 3H-histamine binding to its membrane receptors/transporters of the heart cells and, consequently, to an increase in H-histamine Umax⁡.

In short, extracellular PGE2 induces an increase in cell proliferation via its binding to its membrane receptors, but an increase in intracellular PGE2 induces the activation of the intrinsic pathway of apoptosis by activating Bax.

It has been shown that TNF-α can increase cellular ceramide levels via the de novo pathway as well as by binding to its membrane receptor (TNFR55), causing activation of neutral or acidic SMase [ 36, 42, 43].

In our study, calculated values of Unet, Umax⁡, and backflux (BF) by means of unidirectional paired tracer dilution method may, in fact, represent two events: H-histamine binding to its membrane receptors which leads to lower H-histamine dilution profiles in respect to reference molecule and/or cellular internalization of H-histamine (i.e., cellular uptake) which can be estimated by the BF.

Upon EGF binding to its specific membrane receptor at the cellular surface, EGFR undergoes dimerisation and auto-phosphorylation on multiple tyrosine residues, a key event in the activation of downstream signalling cascades.

Calcium permeability of basophil and mast cell membranes is stimulated on allergen binding to its specific membrane-bound IgE1 3.

Salirasib (Concordia Pharmaceuticals) is an oral RAS inhibitor that causes dislocation of RAS by competing directly with farnesylated RAS in binding to its putative membrane-binding proteins.

So it is possible that upregulation of FasL results in TNF-α-induced death of NB cells by inserting into the cell membrane and binding to its receptor Fas, which is expressed on the membranes of adjacent neurons, and subsequently triggering apoptosis.

Upon binding to its receptors on the cell membrane, TNF-α initiates an inflammatory cascade consisting of increases in COX-2, iNOS, and endothelial adhesion molecule expression, recruitment of inflammatory cells and eventual tissue destruction [20].