Sentence examples for binding to its antigen from inspiring English sources

To confirm that the cell surface-anchored PS11-scFvFc remains functional for binding to its antigen, 293T cells transfected with different PS11-scFvFc-TM fusion proteins were stained with a biotinylated-TRM peptide and analyzed by FACS, using APC-conjugated streptavidin.

First, the internalization kinetics of the MG1 binding to its antigen were determined.

A commercial ELISA kit (Bio-Rad Platelia Kit; Bio-Rad, Hemel Hempstead, UK) was used to investigate recombinant antibody binding to its target antigen.

The strategy allows for the generation of a homogeneous ADC product via functional, antibody interchain disulfide-bridging that displays retention of binding to its target antigen.

Immunocytokines are expected to exert their therapeutic activity by extravasation from blood vessels at sites of disease, followed by antibody binding to its cognate antigen and by a prolonged interaction of the cytokine moiety with leukocytes.

However, only a minor proportion of mAb cU36 internalizes after binding to its target antigen, therefore in the second biodistribution study the anti-EGFR mAb cetuximab was chosen because of the high rate of internalization [ 21].

However, soluble scFvE2/p17 isolated from Sf9 cell lysates was capable of binding to its specific antigen, in the form of a synthetic p17 peptide or as Gag polyprotein-embedded epitope.

This fluorescence diffusion pattern indicates that both the scFv3G1 and the parental MAb3G1 can be efficiently internalized into the cytoplasm following binding to its target antigen HTNV GP on the surface of HTNV-infected cells.

Only a minor proportion of mAb cU36 internalizes after binding to its target antigen, therefore in the second biodistribution study, the anti-EGFR mAb cetuximab was chosen because of the high rate of internalization.

VCAM-1 is expressed on activated endothelial cells and stimulates transendothelial cell trafficking by binding to its ligand, very late antigen (VLA -4 on T cells and monocytes [ 41].

CSF1 acts via specific binding to its high-affinity receptor CSF1R (CD115 antigen), encoded by the c-fms proto-oncogene.