Sentence examples for binding to integrins from inspiring English sources

Although it does not possess an Arginine Glutamate Aspartate (RGD) domain, a classical structural element for binding to integrins, POSTN also been reported to bind to αV β5 and αV β3 integrins to coactivate EGFR signalling that modulates cell motility and proliferation (Yan and Shao, 2006).

RGD tripeptide motifs frequently mediate ligand binding to integrins.

Adsorbed proteins play a major role in the attachment of anchorage-dependent cells through their binding to integrins [25].

Both viruses had expanded tropisms, and efficiently entered target cells via binding to integrins, but also retained their native tropisms for CD46 and signaling lymphocyte activation molecule (SLAM).

Using phage display we selected several CTLA-4-based variants capable of binding to human αvβ3 integrin, one of which showed binding to integrins in situ.

In addition, rLj-RGD3 could inhibit the adhesion of HeyA8 cells to extracellular matrix proteins by competitively binding to integrins, indicated that rLj-RGD3 might act as an anti-tumor drug to treat ovarian carcinoma patients in the future.

This result suggests that tumor uptake of the hybrid probe was attributable to its binding to integrin αVβ3.

The effect of SB might be related to its binding to integrin α2β1, the possible direct target protein of SB found in our previous study [9].

Signal cascades after SB binding to integrin α2β1 might be important basis for the inhibitive effect of SB on platelet adhesion and aggregation.

The engineered knottin peptides were tested for their ability to compete with 125I-echistatin for binding to integrin receptors expressed on U87MG glioblastoma cells, which express ∼105 αvβ3 integrin receptors per cell [26].

Ligand binding to integrin controls adhesion-dependent proliferation, whereas unligated integrins enhance apoptotic pathways [ 2].