Sentence examples for binding to imperfect target from inspiring English sources

MicroRNAs function in post-transcriptional gene silencing by binding to imperfect target sites in messengerRNAs.

miRs are small noncoding RNAs that influence translation through the binding to imperfect, complementary sites on the target mRNA.

In animals, miRNAs have regulatory effects through their binding to imperfect complementary sites within the 3'-untranslated regions (3'UTRs) of their mRNA targets.

16, 21 miRNAs may also bind to imperfect complementary sites within the 3′ untranslated regions (3′UTR) of mRNA targets resulting in translational inhibition of gene expression.

(This may be due to imperfect program targeting, fluctuations in income and family composition, or the fact that registration information is only updated every two years).

Target prediction is difficult because of the very short length of the mature miRNA and the imperfect binding to the target.

miRNAs are ~22-nucleotide small noncoding RNAs that modulate gene expression by binding to target mRNA by imperfect complementary, causing either mRNA degradation or translation inhibition [ 5].

The complementarity of a miRNA binding to a target site is usually imperfect and commonly involves bulges (see Figure 1), which results in gapped alignments.

In these instances of imperfect complementarity, there is often a short, ∼6 8 nt "seed" region, located near the 5′ end of the miRNA, which appears to be of paramount importance in terms of dictating binding to specific target mRNAs [1].

The amino (N -terminal regioN -terminal4 contain the conseregion2R3 imperfect repeats, which are invofved in binding to target DNA SbMYB44es [see Supporting Information— Fig. S1 ].

It seems to work by binding to multiple targets, she said, which may slow down the development of resistance.