Sentence examples for binding to hypoxic cells from inspiring English sources

Immunostaining with pimonidazole did only show a tendency for decreased binding to hypoxic cells in the short-term study.

While activation of the complement system after binding of MBL to hypoxic cells with subsequent killing and opsonophagocytosis of these cells might seem plausible, a recent study has shed light on a new mechanism independent of complement activation [ 43].

These results indicate that glucose concentrations lower than 5 mM can decrease the HMP rate and the toxicity and binding of MISO to hypoxic cells, and imply that calibration curves with normal and low glucose concentrations should be used to estimate the possible hypoxic fraction when MISO is used as a hypoxic probe in vivo.

The selective binding of [F]FMISO to hypoxic cells has been demonstrated in vitro as well as preclinically in vivo (Rasey et al, 1989; Koh et al, 1992).

The binding of ring-labelled and side-chain labelled misonidazole to hypoxic cells in monolayer and spheroid cultures of mammalian cells has been compared.

TPZ, a bioreductive drug, is selectively toxic to hypoxic cells [26].

It is more toxic to aerobic than to hypoxic cells.

Differential metabolism under oxic compared to hypoxic conditions results in SR 4233 exhibiting selective cytotoxicity to hypoxic cells.

The rate of binding to chronically hypoxic cells at the edge of the necrotic centre was 20 times less than to similar cells in other spheroids made maximally hypoxic with N2.

We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with pan-genomic analyses of hypoxia-inducible factor (HIF) and RNApol2 binding in hypoxic cells.

In the control group and treatment group with either X-irradiation or TAS106 alone, few apoptotic cells were observed, among the pimonidazole-binding hypoxic cells.