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The envelope E2 glycoprotein plays a critical role in the initiating infection through recognizing and binding to human cellular receptors [16] [20].
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Most Opa proteins mediate invasion of human cells via binding to human carcinoemybryonic cellular adhesion molecules (CEACAMs) [13].
LRP1 was originally identified as an endocytic receptor; albeit it is now evident that ligand binding to human LRP1 engages specific signaling pathways promoting downstream cellular responses (May et al, 2005; Shi et al, 2009).
To initially evaluate the compatibility of hydroxy-Pdots with a complex cellular environment, we established specific binding to human cells through chemical targeting.
Musunuru, K. Genome editing of human pluripotent stem cells to generate human cellular disease models.
One way is to use human cellular structures as a metaphor for economic growth.
This makes it difficult to interpret human cellular studies.
Similarly, trypsin treatment of the nanosensor coated with cellular membranes abolished AH peptide binding to the cellular membranes but did not affect the binding of a control lipid-binding peptide.
Passive immunisation with antibodies binding to the cellular prion protein (PrPC) can protect against prion disease.
These properties are characteristic of signal transduction induced via ligand binding to the cellular receptor, lipoprotein receptor-related protein.
Here, we show that it is possible to obtain monomeric scFvs binding specifically to human papillomavirus type 16 E6 and cellular gankyrin oncoproteins in quantities higher than 0.5 g/L of shake-flask culture in E. coli cytoplasm after auto-induction.
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