Sentence examples for binding to human CD1d from inspiring English sources

By characterizing a large number of molecular species within the CD1d ligand pool, our analysis provides new insights into the structural characteristics of ligands that are selected for binding to human CD1d.

To gain insight into the characteristics of lipids selected for binding to human CD1d, we analyzed the length and numbers of double bonds of carbon chains from diacylated ligand species.

To test the efficiency of JL2 binding to human SCARB2, the JL2 mAb and isotype control mAb were diluted in complete DMEM at the indicated concentration.

Using phage display we selected several CTLA-4-based variants capable of binding to human αvβ3 integrin, one of which showed binding to integrins in situ.

Although the neonicotinic compounds fully inhibited binding of both [α-125I]bungarotoxin to human α7 nAChRs and [3H]cytisine to human α4β2 nAChRs, they were markedly more potent at displacing radioligand binding to human α4β2 nAChRs than to α7 nAChRs.

These compounds were evaluated for binding to human AT1 receptor and for ANG II antagonism in vitro on isolated rat uterus.

A general loss of binding to human Hsp90 was observed, except for replacement of the carbamate with a hydroxamate group which gave an analog with weak activity.

Binding to human BH3-like peptides showed that KSBcl-2 has similar specificity to Mcl-1, and BHRF1 has a restricted binding profile; M11 binding preferences are distinct from those of Bcl-xL, Bcl-2, and Bcl-w.

The peptide sequence GCRGDCL – a disulfide-bridged cyclic heptapeptide that confers binding to human αvβ3 integrin was introduced into AB, CD and/or EF loops and single and double mutants were heterologously expressed in Pichia pastoris.

In searching for a novel CCR3 receptor antagonist, we designed a library that included a variety of carboxamide derivatives based on the structure of our potent antagonists for human CCR1 and CCR3 receptors, and screened the new compounds for inhibitory activity against 125I-Eotaxin binding to human CCR3 receptors expressed in CHO cells.

Measurement of rCR2 binding to human C3d was performed according to a standardized ELISA protocol.