Sentence examples for binding to host transporter from inspiring English sources

Infected cell protein 47 (inhibitsnhibits MHC Ⅰ antigen presentation pathway by binding to host transporter associated with antigen presentation (TAP), and thereby attenuates of specific cytotoxic T lymphocytes (CTLs) responses and evades the host immune clearance.

We therefore initiated a 3D-QSAR study to develop predictive models for compound binding and identify structural features important for binding to this transporter.

Both epileptic groups presented elevated binding to the dopamine transporter and low tissue content of dopamine and its metabolites.

In addition, monoamine transporters share substrates and high affinity inhibitor compounds (such as mazindol) commonly used to study drug binding to the transporters.

Substrate recognition models that we previously published for this transporter class showed that the purine 2-position is not utilized in binding to trypanosomatid nucleobase transporters, whereas it is engaged in hydrogen bond formation in human nucleobase transporters (19, 27).

Data mining using resources like Metrabase can be employed to understand, for example, transporter function or the promiscuous nature of compounds binding to transporters competitively or non-competitively.

One suggestion is that cannabis and cannabinoids increase the amount of free dopamine in the brain by preventing the dopamine from binding to another neurochemical dopamine transporter.

We have now characterized ligand binding to the full-length transporter OpuA and to isolated OpuAC (see Fig. 1A).

FimH mediates binding to mannose containing host receptors.

Moreover, we show that the association of NP with the host transporter does not impair the binding of NP to RNA.

(F) The down-regulation of 5-HT2AR does not attenuate the binding of HCV to host cells.