Sentence examples for binding to genomic sequences from inspiring English sources

We suggest therefore that the competition between TFs with histones for nonspecific binding to genomic sequences might be an important mechanism influencing nucleosome-binding preferences in vivo.

These data further support the tissue-specificity of Twist1 binding to genomic sequences detected by ChIP-Seq in ECC, Limb buds, and PNST cells.

Collectively, these ChIP-seq experiments demonstrate extensive Twist1 binding to genomic sequences and indicate that Twist1 bound predominantly in a tissue-specific manner, with much smaller numbers of shared binding regions detected among ECCs, limb buds, and PNST cells.

Primer sets "1" and "2" were used in PCRs with genomic DNA, and secondary PCRs were done with primer sets "1' " and "2' " to eliminate non-specific binding to genomic DNA sequences.

Furthermore, applying the CSI binding data to genomic sequence (genomescapes) provides a powerful tool for identification of potential in vivo binding sites of a given DNA ligand, and can provide insight into differential regulation of gene networks.

Anti-gene ONs (AGOs) act by sequence-specific binding to genomic duplex DNA.

The STAT DNA interaction has also been disrupted by 'decoy oligonucleotides' that contain STAT-binding sequences and competitively inhibit STAT binding to genomic DNA.

Primers were based on published mRNA sequences and were designed to span at least two exons in order to avoid binding to genomic DNA.

As a demonstration of how our method works, we apply our approach to genomic sequences around the Hox gene cluster and to a set of DNA-binding proteins.

However, universal PBM data are not suitable to predict binding of a TF to longer genomic sequences.

This observation not only allows but also requires us to identify potential miRNA binding sites from genomic sequences of single organism, as implemented here.