Sentence examples for binding to further from inspiring English sources

Combination of these regions synergistically modifies DNA binding to further enhance specificity.

In this study, we aimed towards the development of novel 18F-labeled PSMA inhibitors, exploiting optimized 18F-labeling strategies and the increasing experience concerning the structural requirements for optimal ligand binding to further improve the in vitro and in vivo PSMA-targeting characteristics in comparison to the currently available 18F-labeled compounds.

If a large excess of dT50 is included in the ATP solution, it acts as a trap for PcrA after it dissociates from the fluorescent DNA and thus prevents binding to further substrate fluorescent DNA.

We found that relative to the wild-type receptor, enhanced binding to Grb2 further increases the incorporation of bromodeoxyuridine and the expression of Twist, while decreasing that of p27Kip1 and myogenin.

Finally, we anticipate that other factors, including receptor hetero-dimerization, preferential interactions of GPCRs with particular membrane lipids, lipid raft dynamics and actin cytoskeleton re-arrangements, receptor cross-talk and G-protein independent pathways such as β-arrestin binding to receptors further increase the possible range of outcomes of this signaling system [52], [68] [73].

MEME also detected GATA2 binding to a further GATA variant, wGATAAsA, in E cells.

This mechanism could work in synergy with activated ERs to facilitate FOXL2 binding to TESCO, further suppressing SOX9 mRNA production as recently suggested in goats [ 38].

In the second stage of activation, a suitable substrate can now exploit the primed Sec61 by binding to and further opening the lateral gate.

Recent evidence that mesothelin may promote cell-cell adhesion in ovarian cancer through heterotypic binding to CA125/MUC16 further supports a role in tumor progression [ 11].

HDACs also interact with other epigenetic modifiers such as DNA binding proteins and methyl-binding proteins to further modify gene expression.

While the cell binding continued to further increase with time, the increase was modest beyond 120 min incubation.