Sentence examples for binding to fibrillar matrix from inspiring English sources

For example, Evanko et al. reported that HA controls fibrosis by binding to fibrillar matrix components.

Despite selection against monomeric Aβ40, these aptamers showed binding to fibrillar Aβ40.

The association rate constant (ka) of various Aβ derivatives binding to fibrillar Aβ40 varied between 31 to 55 M-1s-1.

By ELISA, scFv-6E exhibits conformation-specific binding to fibrillar α-synuclein but not monomeric or oligomeric species [22].

The reported binding constants (Kds) for gantenerumab binding to fibrillar Aβ, soluble Aβ oligomers, and Aβ monomer are 0.6, 1.2, and 17 nM, respectively [ 215].

Consistent with its high-affinity binding to fibrillar Aβ, gantenerumab caused a significant, dose-dependent reduction in amyloid plaques in human AD brain tissue [ 215].

More recent studies show that ponezumab labels amyloid plaques in 14-month-old Tg2576 mouse and human AD brains [ 207], demonstrating binding to fibrillar Aβ.

We also assessed temporal changes of actin polymerization using transgenic mice expressing EGFP-tagged Lifeact, a short peptide specifically binding to fibrillar actin.

These results emphasize the crucial role of GPO triplets for gelatinase binding and established a 10-fold molar excess of (POG 5 in relation to proMMP-2 as a minimum prerequisite for blockade of proMMP-2 binding to fibrillar CI.

Since binding to the extracellular matrix influences the activity of both gelatinases, here the role of fibrillar collagens as the most abundant matrix components in fibrotic tissue was investigated.

Analysis of elevated regions of permeability suggested that 125I-LDL was binding to the extracellular matrix.