Sentence examples for binding to extracellular matrix from inspiring English sources

As can be seen in Fig. 6, the PEGylated construct's passivation and reduced nonspecific binding to extracellular matrix is clearly advantageous, with the construct being taken up by cells throughout the spheroid.

GDNFv is an engineered form of GDNFwt, expressed and purified from mammalian cells, designed to overcome these limitations, including removal of the N-terminal heparin-binding domain to improve its diffusivity in brain parenchyma by reducing its binding to extracellular matrix (ECM), and key amino acid substitutions to improve chemical stability.

One proposed mechanism for the increased metastatic potential is binding to extracellular matrix components, enabling invasion and angiogenesis [19, 20].

This increased uptake may be caused by accumulation of VEGF in the tumor, due to high paracrine expression and subsequent binding to extracellular matrix glycoproteins such as heparan sulfate proteoglycans (HSPG) and neuropilins (NRP).

Previous studies have shown that Vsp2 appears to be more "sticky" than Vsp1, as shown by its greater binding to extracellular matrix components like heparin and dermatan sulfate [13].

Integrin binding to extracellular matrix increases tyrosine phosphorylation of focal adhesion kinase (FAK).

They are able to contribute to microbial adhesion by binding to extracellular matrixes (ECMs) of host cells and initiate infection [1].

It has been demonstrated that APP is engaged in neuronal growth cone adhesion and plays a role as an independently operating cell adhesion molecule for binding to extracellular matrices such as laminin [ 6].

Interestingly, APP is also known to promote cell migration in neuronal progenitor cells [ 16] and engage in neuronal growth cone adhesion where it plays a role as an independently operating cell adhesion molecule for binding to extracellular matrices such as laminin [ 6].

The microarray contained 220 probes for genes encoding antibiotic resistances, hemolysins, toxins, amino acid decarboxylases (e.g. biogenic amine formation), binding proteins to extracellular matrix (ECM), lipases, proteases, stress response factors, or nitrate dissimilation.

Cell adhesion is mediated through transmembrane molecules binding either to extracellular matrix or to adjacent cells.