Sentence examples for binding to engage from inspiring English sources

This observation is sound, as IDPs frequently use motif binding to engage with their binding partners (Kragelj et al., 2015; Schneider et al., 2015; Tompa and Fuxreiter, 2008; Wright and Dyson, 2009).

Does Kaiso use the same binding mode to engage methylated DNA and its non-methylated target?

For these bivalent analogues with rigid linkers, the nature of the linker did not have a profound effect on function: in each case, the EC50 values were comparable to those of the corresponding monovalent controls (either 11 or 12) and, consequently, it is unlikely that the linkers allow the binding groups to engage with the MetJ dimer in a bivalent sense.

The two additional disulfide bonds on both sides of the Ca2+-binding loop stabilize this surface and project the ice-binding residues to engage with the ice lattice.

Other antibodies were shown to utilize different regions of the antigen-binding site to engage various antigens without involving significant structural plasticity [12], [13], [19], [21].

Some SH2 domains feature a secondary site located outside of the primary ligand-binding site to engage a pTyr-ligand protein using two sites [ 76, 80].

Myxoma virus M11L was shown to adopt the classical Bcl-2 fold that utilizes the canonical Bcl-2 homology 3 (BH3 -binding groove to engage BH3 -bindingto exert its pro-survival effect.

Two NES binding sites poised to engage two Rev NES peptides are shown in cyan.

Properdin is capable of binding to bacteria to engage the alternative complement pathway and its importance in host defence is illustrated by the enhanced sensitivity of properdin-deficient patients to meningococcal disease (Densen et al., 1987; Emonts et al., 2003).

(D ) Alignment of the C-terminal most residues of the conserved functional core of human PPP1R15B (R15B) and mouse PPP1R15A (R15A) with amphipathic helices of G-actin binding proteins seen to engage the cleft between domains I and III in the indicated PDB files (shaded grey).

The only other actin-binding protein shown to engage this region of actin in a similar manner is the structurally unrelated DBP (Otterbein et al, 2002; Verboven et al, 2003) (see Discussion section).