Sentence examples for binding to endothelial cell from inspiring English sources
Fibulin-5 binding to endothelial cell (EC) surface integrins may effect cell proliferation and cell attachment to extracellular matrix (ECM) or to artificial surfaces.
Although it is commonly accepted that endothelin-1 binding to endothelial cell ETB receptors stimulates nitric oxide (NO) synthesis and subsequent smooth muscle relaxation, the signaling pathways downstream of ETB receptor activation are unknown.
PfEMP1, expressed during maturation by trophozoite (blood stage) and early gametocyte (transmission stage) parasites [15], mediates binding to endothelial cell receptors in the deep vasculature of host tissues [13], [14].
TSP1 binding to endothelial cell CD36 receptors, or other receptors such as CD47, leads to downstream apoptosis [ 24, 25].
Kallistatin, through its heparin-binding site, inhibits TNF-α and HMGB1-induced inflammation by antagonizing their binding to endothelial cell surfaces [ 21, 25].
For future studies, flow-based systems examining IE binding to endothelial cell lines probably provide the most physiologically relevant approach, and allow investigation of rolling as well as static adhesion, and synergism between receptors that might be important in vivo (Ref. 52).
5 Bevacizumab is a humanized monoclonal antibody against the VEGF-A ligand that binds to its circulating target, altering the kinetics of ligand binding to endothelial cells and downregulating angiogenesis.
Nevertheless, the diabetic mice had significantly lower uptake of 99mTc-HYNIC-RGD in the ischemic limb compared to the non-diabetic mice, suggesting that the binding to endothelial cells in this model had the dominant effect.
