Sentence examples for binding to enable from inspiring English sources

The ability of confirmed in vivo TF binding to enable CRM discovery has been clearly demonstrated by ChIP-based studies [e.g. [ 25- 28] (although even in vivo binding does not necessarily connote function [ 29], and computational predictions can sometimes outperform ChIP-based ones [ 30]).

The two functions can be separated in vitro by mutations that retain sufficient PP1 binding to enable reliable measurement of the non-specific phosphatase activity of the binary PPP1R15-PP1 complex and all but eliminate actin's ability to promote substrate specificity.

A possible role for Gln42 is in shaping the binding pocket to enable the substrates to bind although we cannot exclude that it affects the binding of the nearby sodium ion.

Alternatively, the acquisition of new binding sites to enable the upstream control could in some occasions interfere with the autoregulatory binding site.

The input samples were incubated for the same duration and temperature as the binding reactions to enable direct comparison.

Primers were designed with 15 bp homologous to the multiple cloning site of pGL3 with restriction enzyme binding sites to enable cloning of the rSAA4 promoter fragment into pGL3 (Supplemental Table VII).

The ongoing expansion of public [40, 46 49] and proprietary [50] target-ligand binding data begins to enable "machine learning" prediction of target inhibition profiles [51 56].

Juvenile hormone itself may be bound by JH binding proteins (JHbp) to enable immobilisation, regulate degradation or enable transport [ 28].

Therefore, we investigated whether IgG antibody binding to capsule enabled SP-A binding to C. neoformans.

The two dimerisation domains, that is the DNA binding domain (DBD) and ligand binding domain (LBD) work in tandem to enable DNA binding.

Together these results (summarized in Table 1) suggest that PDE4D5 binding to RACK1 is necessary to enable high-affinity binding of PDE4D5 to its substrate cAMP, and for effective inhibition by rolipram in the particulate fraction of HEK-293 cells.