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SLRPs are capable of binding to different types of collagen [34], [35], thereby regulating fibril assembly and organization, degradation, and quantitative and functional aspects of the collagen network [33].
Since the membrane-binding properties of α-Syn are thought to be relevant for its pathologic activity [1], [9], [10], we speculated that also for synphilin-1 the binding to different types of lipid structures could be linked to its inclusion formation.
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Particularly, CaM binds to different types of target binding motifs, where the hydrophobic residues are separated by 1 10, 1 14 and 1 16 residues [11].
We found that this fragment could inhibit VEGF binding to different cell types and block VEGF-induced endothelial cell migration.
However, there was statistically significant variation in binding to different host cells types.
Second, although implicating Hdm2 as an essential regulator of the activity of TAp53/Δ40p53 hetero-oligomers, our study has not quantified variations in the binding of Hdm2 to different types of hetero-oligomers and has not clearly identified the consequences on p53 protein stability.
It works by binding to DNA leading to different types of DNA lesions and subsequently inducing apoptosis (Galluzzi et al, 2012).
At several points in evolutionary history, novel gene types have arisen to encode proteins in which DNA-binding ZNF motifs are tethered to different types of chromatin-interacting or "effector" domains.
A review study summarized the types of protein binding to different nanoparticles to determine the composition of protein corona [40].
Dopamine (DA) is a simple organic chemical in the catecholamine family released from postganglionic nerve fibers of the superior cervical dopaminergic ganglion in the aqueous humor [ 9– 12] and exerts its action by binding to 5 different types of DA receptors (DA1 5) which belong to the superclass of G-proteins coupled receptors.
Taking into account that peptide 11438 sequence belongs to the gH binding region we were interested in determining the binding of these peptides to different type of cells.
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