Sentence examples for binding to different target from inspiring English sources
CRYAB has been shown to perform protective function in cardiomyocytes by maintaining sarcomeric elasticity, mitochondrial integrity and also homeostasize redox imbalance by binding to different target molecules.
Thus, target recognition of RISCs follows the diffusion-controlled model, where antisense strand-guided RISCs are continuously binding to different target mRNAs.
HPep1 and HPep6 inhibited binding of LPS to LBP and HMGB1 by binding to different target sites on LPS, and further evaluation is necessary to determine whether combined treatment with both peptides can inhibit LPS-mediated TNF-α production to a greater extent than treatment with each peptide alone.
Another possibility is that Smarca1 and other SWI/SNF factors might facilitate Foxa1/2 binding to different target sites in neurons at distinct phases of their maturation to allow for gene expression through promoting an open chromatin state at these targets.
It is generally assumed that the recognition and binding by IDPs/IDPRs involves their folding into a specific structure, and that advantages of IDP/IDPR as signaling hubs are their adaptability, promiscuity, and ability to fold differently upon binding to different targets.
They take up different structures upon binding to different targets, and thereby exhibit functional flexibility through the formation of fuzzy complexes [2].
Lack of intrinsic structures could render protein additional functions, including binding to different targets [ 4], transcriptional regulation, translational regulation, and cellular signal transduction regulation [ 5].
These unstructured regions can adopt different conformations to facilitate binding to different host target proteins.
Promiscuity of the compound 5 was further confirmed by in silico binding to different antibacterial targets.
The rationale for combining taxanes and estramustine is to achieve greater inhibition of microtubule function and cytotoxicity by binding to different protein targets in the same microtubular system.
The use of iSPR for monitoring autoantibody binding to different citrullinated targets was first described by Lokate and coworkers [ 22], and later citrullinated B-cell epitopes in fibrinogen were successfully mapped with the use of this technology [ 23].
