Sentence examples for binding to different isoforms from inspiring English sources
Figure 5C demonstrated that sera were binding to different isoforms of CRMP-2.
Results also show that unstructured post-translationally modified C-terminal tails are responsible for the dynamics of Sm-B/B' and U1-C and that their interactions with the Sm core are controlled by binding to different U1-70k isoforms and their phosphorylation status in vivo.
It activates gene expression via direct binding to different nuclear receptors that are expressed as various isoforms during embryogenesis.
We report here the first systematic comparison of ABTS-binding to different proteins, i.e. the four isoforms of Trametes versicolor, using a combination of sequence clustering, density functional theory calculations, homology modeling, and multiple induced-fit docking protocols at variable pH-dependent protonation states and T1-copper oxidation state.
Earlier biochemical in vitro studies suggest that each Dscam1 isoform has extracellular domains that prefer to bind to itself (self-binding or homophilic binding), while heterophilic binding (binding between different isoforms) tends to be weak or below the detection limit of the assays used [ 9].
The schematic Figure 1 summarizes the effects of CXCL10 on different cell types after binding to the different CXCR3 isoforms in both mouse and human.
Although several Cyp inhibitors have been reported in the literature, it has proven challenging to achieve high binding selectivity for different isoforms of this protein family.
Through interactions with different co-factors, mediated by alternative protein domains, or even through differences in the sequence recognition specificity of the DNA-binding domain, the different isoforms may regulate different sets of genes.
We compared the predicted self-binding affinities of different isoforms based on the information derived from both the ancestral and current genomes.
Alternative splicing gives rise to many different isoforms.
The specificity of binding of Ig isotypes to different FcR isoforms and allotypes is complex, with both CH2 regions 234-237 and the CH2/CH3 interface being implicated [ 21].
