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Therefore the two states, PRC-repressed and active, exist separately within a cell (binding to different alleles) or cell population.
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NF-κB dimers bind to different κB sequences with different binding affinities and binding modes.
Additionally, we performed in silico screening of the 5'-regulatory region of GHSR and evaluated SNPs disrupting putative transcription factor (TF) binding sites in vitro with gelshift assays to determine differences in protein binding between different alleles of SNPs.
Thus, the gelshift bands might be stronger or weaker comparing males and females but the clear difference of protein binding to the different SNP alleles will still occur.
The trees enable us to test if there is any apparent similarity in peptide binding between different alleles that have previously been associated with DILI, which might indicate a common functional pathway.
for MHC Class I and Class II associated T cell epitopes on PAL, which predicts which sequences are associated with binding to several different HLA alleles, a requirement for antigen presentation and subsequent primary immune response.
Therefore, we measured CTCF binding to the different IC1 alleles by the Chromatin ImmunoPrecipitation (ChIP) assay with anti-CTCF antibodies in transfected Hep3B cells.
Alignments of all known germline sequences assigned to the different alleles are displayed under the nucleotide and amino acid sequences.
These two mutants appear to be different alleles of the same gene.
SSR markers revealed 2 to 26 different alleles and an average of 12.45 alleles per locus.
It can be detected with different fluorophores or sequencing to distinguish different alleles.
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