Sentence examples for binding to define from inspiring English sources

In the current paper, we use I-PFO* binding to define three pools of cholesterol in the PM.

The stability of some mRNAs is influenced by degradation, regulated in part by specific proteins binding to defined AU-rich base sequences (ARE elements) in the 3' untranslated region [34].

For a quantitative determination of binding affinities, it is important to study the binding to defined bile aggregates.

Their binding to defined regions in the genome determines the rate at which their target genes are transcribed.

RNA processing factors can be recruited to transcribed genes in multiple, not mutually exclusive, ways: i) by binding to the DNA template either directly or through recruiting factors, ii) by binding to processing signals present in the nascent RNA and iii) by binding to defined regions of the RNAPII elongating complex i.e. CTD [ 60].

Most such binding predictions are based on machine learning algorithms, which aim to generalize experimental binding data to define a binding sequence pattern for a given MHC molecule.

PARalyzer [ 89] uses the number of T → C conversions that are diagnostic of PAR-CLIP binding sites to define the limits of the binding site using a kernel density-based classifier, but does not use transcript abundance data and so generates a set of RBP-bound sites rather than RBP target preferences.

Successful strategies include making educated guesses based on protein primary sequence, using binding studies to define sites of protein-protein interaction, and designing peptides based on the three-dimensional structure of known sites of interaction.

The dead-end elimination and A∗ search algorithms were used here to find all low-energy single mutant variants, and corresponding structures of a G-protein heterotrimer, to measure changes in structural stability and binding interactions to define a protein fitness landscape.

Using molecular modelling and the structure of the weak inhibitor 5-aminoiso quinolin-1-one, 3-aryl-5-substituted-isoquinolin-1-ones were designed as inhibitors to explore the structure activity relationships (SARs) for binding and to define the shape of a hydrophobic cavity in the active site.

As it gets narrowed down, overlapping peptides could be used in binding assays to define the boundaries.