Sentence examples for binding to cellular partners from inspiring English sources
EWS/FLI1 functions by binding to cellular partners in transcription and splicing, similar to the cellular machinery corruption by virus for virion production [ 55].
(A ) Lam4S2 binding to cellular lipids (see Figure 2A ).
This consensus sequence has also been referred to as an LXXLL motif [ 20, 21] to highlight the importance of the three conserved leucines at positions 9, 12, and 13 in facilitating E6 binding to its cellular partners, as substitution of these leucines has been reported to abolish E6/E6-AP interaction [ 7].
Consequently, this protein is not a regulatory PR72/B" subunit strictu senso [ 7] but-based on its sequence-might compete in binding to other cellular partners of PR130.
This is due to some strong electrostatic bindings to cellular membranes.
The present study aimed at analyzing the molecular and functional properties of primary Vpr proteins isolated from two infected patients, in terms of binding to its known cellular partners, docking at the NE, cytostatic and proapoptotic activities.
EWS/FLI1 functions by binding to normal cellular protein partners in transcription and splicing, similar to virus corruption of normal cellular machinery for virion production [ 55].
The availability of the three-dimensional structure of E6 allows for the visualization of the potential residues that mediate binding to its cellular protein partners.
These questions apply to transcription factors binding to genomic DNA and to protein interaction domains binding to their partners.
Moreover, knowledge of the amino acid sequences that direct binding of HR-E6 to its protein partners further contributes to the potential of developing agents that block E6 binding to its cellular targets, resulting in the possible re-sensitization of HPV-infected cells to normal cell-death-inducing stimuli.
