Sentence examples for binding to cellular integrins from inspiring English sources
The basic domain 49 72 contains an RKKRRQRRR motif, which confers the RNA binding activity of Tat and is also important for cellular uptake and nuclear distribution of this protein [81], while amino acids 65 80 of Tat include the RGD motif that is involved in binding to cellular integrins [81], [82].
Therefore, the free c RGDfK) molecules cannot compete with c RGDfK -Bchl-D binding to c RGDfK -Bchl-Dins in the large tumors.
In contrast, synthetic peptides containing the RGD sequence can compete with adhesive molecules for binding to integrins and disrupt the cellular activity mediated by integrin interaction.
Since proMMP-2 activation is directly associated with the level of MT1-MMP activity, these results indicated that cellular binding to BSP via integrin αvβ3 does not modify MT1-MMP activity on the cell surface.
The AdRGD vector has enhanced binding to αν integrins.
These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand binding to αvβ3 integrins on vascular cells.
Integrin binding to extra-cellular matrix compounds induces outside-in signaling through clustering of integrin heterodimers at focal adhesion sites (Gong et al., 2010; Hynes, 2002).
Additional mechanical unfolding triggers an essential arginine residue, which is required for high affinity binding to integrins, to move to a position far from the integrin binding site.
Although G-BSA is not a ligand for integrin (Fig. 5B), F-BSA caused cellular apoptosis by binding to integrin α5β1 (Figs. 4 and 5).
