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The RGD-motif is a well-described tripeptide, that by binding to cell surface integrins facilitates virus entry into cells.
TNF binding to cell surface receptors mediates its physiologic actions, although the exact mechanism of TNF action is unknown.
This limitation may be overcome by a sweeping antibody construct that has both pH-dependent antigen binding and increased binding to cell surface neonatal Fc receptor.
The apparent half-maximal binding to cell surface ROBO1 was estimated to be approximately 32.5 ng/mL from the fitted curve in ELISA (Figure 1c).
The guanosine triphosphate-binding proteins (G proteins) found in a variety of tissues transduce signals generated by ligand binding to cell surface receptors into changes in intracellular metabolism.
Thus, SE-activated signaling depends on binding to cell surface CRT, which plays a critical role in signal transduction.
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Promastigote stages of Leishmania wild type, ΔLdMT and ΔLdRos3 lines were incubated with different concentrations of duramycin and papuamide B, cytolytic peptides that requires binding to cell surface-exposed PE and PS, respectively, to exert their cytotoxicity [18].
Measurement of the kinetics of antigen binding to cell surface-expressed γδ TCR by real-time FACS analysis was carried out as described (Zeng et al., 2012).
These data show that SfbI-A40-TED adherence to A549 cells under conditions mimicking inflammation depends on thioester-mediated covalent binding to cell surface-associated fibrinogen.
This action is suggested to be regulated via binding to cell-surface receptors (Yang et al., 1998; Annabi et al., 2006).
Consistently, unlike TGEV-S1, PEDV-S1 exhibited no binding to cell-surface expressed APN or to a soluble version of APN.
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