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ELF6::GUS showed binding to broad regions of the FT locus around the transcription start site with strongest binding to region I (Figures 7B).
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These transcription factors show different binding behaviors ranging from sharp peak to broad regions and require different analysis methods and parameter optimizations.
Previous genetic maps [ 3, 4] were sufficient to map QTL to broad regions.
These factors exhibit different types of binding profiles ranging from sharp localized peaks to broad binding regions.
By binding to regulatory regions alongside certain genes, SIRT1 helps dictate those patterns.
sGAG binding to these regions may compete with other molecules within the crowded environment of a FN fibril19 as all three Hep binding regions have multiple binding partners (see Fig. 1).
Each controls the expression of numerous genes by binding to specific regions in the genome.
As the aa454-544 and aa454-630 mutants displayed substantially reduced H3 binding activity, a broad region within the MTA1 C-terminus appeared to be required for H3 binding activity.
Already before treatment, there was robust antibody binding to a broad range of staphylococcal antigens.
The syndrome was mapped to a broad region of the X, spanning from Xp11.4 to Xq22.2.
miRNAs typically downregulate gene expression by binding to the 3' untranslated region of their mRNA targets.
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