Sentence examples for binding to breast from inspiring English sources
Furthermore, when tested on different tumor cell lines phage RMS-P3 showed a very good binding to breast cancer, glioblastoma and melanoma.
The position of the lipid moiety significantly affects the level of IgG production and the optimal binding to breast cancer cell lines expressing carbohydrate antigens on their surface [20].
We have shown lectin binding to breast cancer cell lines by flow cytometry [ 36, 40, 41].
We show that the majority of lysine-dependent plasminogen binding to breast cancer cells is ultimately regulated by plasmin activity and is dependent on the presence of significant levels of active uPA.
This resulted in a 12-fold decrease in the binding affinity of a chimeric antibody with specificity for the TAG72 antigen (Xiang et al, 1995), a >5-fold lower affinity of a humanised anti-ErB2 antibody for binding to breast cancer cells (Carter et al, 1992), and a complete loss of antigen binding of a humanised anti-alpha 4 integrin antibody (Leger et al, 1997).
While no concrete research has linked binding to breast cancer, they can create lumps which, while inherently benign, can lead to expensive, uncomfortable, and ultimately unnecessary testing.
HCAb2 showed punctate membrane staining on MDA-MB-231 cells and preferential binding to human breast tumor tissues in comparison to normal breast tissues.
Human monoclonal antibodies, 27.F7 and 27.B1, to GIPC1 demonstrate specific binding to malignant breast cancer tissue with no reactivity with normal breast tissue.
To determine if HCAb2 reveals selective binding to human breast tumors, a cohort of fresh frozen human breast tissue samples was screened with HCAb2.
Interestingly, the scFvs developed here showed good binding to the breast cancer cell line T47D and ovarian cancer cell line SKOV3, but no binding to the second breast cancer cell line MCF-7.
In addition, the pIX-pK displayed on the Ad capsid could mediate HSPGs dependent binding to human breast cancer cells (AU-565).
